C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 309/04 (2006.01) A61K 31/435 (2006.01) A61P 9/00 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2663263
The present invention is directed to aspartic protease inhibitors represented by the following structural formula (I), or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the aspartic protease inhibitors of Structural Formula (I). Methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using these aspartic protease inhibitors are also disclosed.
La présente invention concerne des inhibiteurs des protéases aspartiques représentés par la formule structurelle suivante (I), ou un de leurs sels pharmaceutiquement acceptables. L'invention concerne également des compositions pharmaceutiques comprenant les inhibiteurs des protéases aspartiques de formule structurelle (I). L'invention concerne également des procédés d'action antagonique contre une ou plusieurs protéases aspartiques chez un sujet qui a besoin d'un tel traitement et des procédés de traitement d'une affection induite par une protéase aspartique chez un sujet à l'aide de ces inhibiteurs des protéases aspartiques.
Baldwin John J.
Cacatian Salvacion
Claremon David A.
Dillard Lawrence W.
Flaherty Patrick T.
Gowling Lafleur Henderson Llp
Vitae Pharmaceuticals Inc.
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