Reverse transcriptase inhibitors

Details Reverse transcriptase inhibitors Reverse transcriptase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/14 (2006.01) A61K 31/16 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2709176

Described herein are novel enzyme inhibitors. In some embodiments, the enzyme inhibitors are reverse transcriptase inhibitors, particularly HIV reverse transcriptase inhibitors. Also described herein are compositions containing them and methods of using them. Thus, the compounds and compositions described herein are useful for the in vitro and in vivo inhibition of HIV reverse transcriptase as a method of treating or preventing HIV, AIDS or related disorders.

La présente invention concerne des inhibiteurs d'enzyme innovants. Selon certains modes de réalisation, les inhibiteurs d'enzyme sont des inhibiteurs de transcriptase inverse, en particulier des inhibiteurs de la transcriptase inverse du VIH. L'invention concerne également des compositions les contenant et leurs procédés d'utilisation. En conséquence, les composés et les compositions décrits dans la description sont utiles pour l'inhibition in vitro et in vivo de la transcriptase inverse du VIH en tant que procédé de traitement ou de prévention du VIH, du sida ou des affections apparentées.

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