Rxr activating molecules

Details Rxr activating molecules Rxr activating molecules

C - Chemistry, Metallurgy

07

D

C07D 277/36 (2006.01) A01N 43/42 (2006.01) A01N 43/78 (2006.01) A01N 43/82 (2006.01) A61K 31/425 (2006.01) A61K 31/47 (2006.01) C07D 215/16 (2006.01) C07D 215/20 (2006.01) C07D 215/36 (2006.01) C07D 271/06 (2006.01) C07D 271/07 (2006.01) C07D 271/12 (2006.01) C07D 277/20 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2473156

Disclosed are molecules that activate an RXR receptor, wherein the molecule comprises an RXR binding portion which binds the RXR receptor and comprise a side pocket contacting residue which contacts a side-pocket 1 of an RXR receptor.

Cette invention concerne des molécules qui activent un récepteur RXR. La molécule comprend une partie de liaison avec RXR qui se lie au récepteur RXR et un résidu de contact avec poche latérale qui est en contact avec une poche latérale d'un récepteur RXR.

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