S-hydroxynefazodone

Details S-hydroxynefazodone S-hydroxynefazodone

A - Human Necessities

61

K

A61K 31/496 (2006.01) A61P 3/04 (2006.01) A61P 25/00 (2006.01) A61P 25/06 (2006.01) A61P 25/18 (2006.01) A61P 25/20 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07D 249/12 (2006.01)

Patent

CA 2369225

The S-isomer of the hydroxy metabolite of nefazodone, S-hydroxynefazodone, is an effective treatment for depression which does not give rise to the adverse effects associated with nefazodone. S-hydroxynefazodone is also useful in the treatment of migraine headaches, panic disorders, post traumatic stress disorder and sleep disorders.

L'invention concerne l'isomère-s du métabolite hydroxy de la néfazodone, ou S-hydroxynéfazodone, lequel constitue un traitement efficace contre la dépression ne provoquant pas les effets secondaires associés à la néfazodone. La S-hydroxynéfazodone est également utile pour le traitement des migraines, des attaques de panique, des états de stress post-traumatique et des troubles du sommeil.

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