S-triazolyl .alpha.-mercaptoacetanildes as inhibitors of hiv...

C - Chemistry – Metallurgy – 07 – D

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C07D 249/12 (2006.01)

Patent

CA 2578068

A series of S-triazolyl .alpha.-mercaptoacetanilides having general structure (1) are provided, where Q is CO2H, CONR2, SO3H, or SO2NR2. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.

Une série de S-triazolyl a-mercaptoacétanilides de structure générale (1), dans laquelle Q désigne CO2H, CONR2, SO3H, ou SO2NR2. Les composés inhibent différentes variantes de la transcriptase inverse du VIH, et servent au traitement d'infections VIH.

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