Sabcomeline alone or combined with a mood stabilising or...

Details Sabcomeline alone or combined with a mood stabilising or... Sabcomeline alone or combined with a mood stabilising or...

A - Human Necessities

61

K

A61K 31/439 (2006.01) A61K 31/19 (2006.01) A61K 31/197 (2006.01) A61K 31/4515 (2006.01) A61K 31/4545 (2006.01) A61K 31/496 (2006.01) A61K 31/519 (2006.01) A61K 31/53 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61K 31/554 (2006.01) A61K 31/7048 (2006.01) A61K 33/00 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01)

Patent

CA 2592468

The invention relates to the use of sabcomeline or a pharmaceutically acceptable salt thereof in monotherapy for the treatment of bipolar disorder or mania or and to adjunctive and simultaneous combination therapies for the treatment of bipolar disorder or mania in which sabcomeline or a pharmaceutically acceptable salt thereof and at least one other mood stabilizing or antimanic agent are administered adjunctively or simultaneously. The invention provides methods of treatment of bipolar disorder or mania utilizing such monotherapy and such adjunctive or simultaneous therapeutic combination therapies, therapeutic combinations for use therein and pharmaceutical compositions comprising them.

La présente invention concerne l'emploi de la sabcoméline ou d'un sel de qualité pharmaceutique de la sabcoméline dans le cadre d'une monothérapie pour le traitement de troubles bipolaires ou de manies, ou dans des thérapies combinatoires séquentielles ou simultanées pour le traitement de troubles bipolaires ou de manies, dans lesquelles la sabcoméline ou un sel de qualité pharmaceutique de la sabcoméline, ainsi qu~un autre agent stabilisant l'humeur ou un agent antimaniaque sont administrés de façon séquentielle ou simultanée. La présente invention décrit des méthodes de traitement de troubles bipolaires ou de manies impliquant une telle monothérapie et de telles thérapies combinatoires séquentielles ou simultanées, ainsi que des combinaisons thérapeutiques pouvant être employées dans ce cadre et des préparations pharmaceutiques comprenant lesdits composés.

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