Segmentation and data mining for gel electrophoresis images

Details Segmentation and data mining for gel electrophoresis images Segmentation and data mining for gel electrophoresis images

G - Physics

06

T

G06T 5/00 (2006.01) G06T 7/00 (2006.01)

Patent

CA 2531126

A segmentation method is provided for the automated segmentation of spot-light structures into D images allowing precise quantification and classification of said structures and said images, based on a plurality of criteria, and further allowing the automated identification of multi-spot based patterns present in one or a plurality of images. In a preferred embodiment, the invention is used for the analysis of 2D gel electrophoresis images, with objective of quantifying protein expressions and for allowing sophisticated multi-protein pattern based image data mining, as well as image matching, registration, and automated classification.

L'invention concerne un procédé de segmentation permettant de segmenter automatiquement des structures de taches lumineuses en images 2D, ce qui permet de quantifier et de classifier ces structures et ces images en fonction d'une pluralité de critères, et d'identifier automatiquement des motifs à base de taches multiples présents dans une ou plusieurs image(s). Dans un mode de réalisation préféré, l'invention sert à analyser des images 2D d'électrophorèse sur gel dans le but de quantifier des expressions de protéine et favorise l'exploration de données d'image à base de motifs sophistiqués multi-protéines ainsi que la correspondance de ces images, leur enregistrement et leur classification automatique.

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