Selected cgrp antagonists, methods for the production...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/551 (2006.01) A61P 25/06 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2558889

The invention relates to CGRP antagonists of general formula (I), in which A, X, D, E, G, M, Q and R1 to R3 are defined as in Claim 1, to their tautomers, isomers, diastereomers, enantiomers, hydrates, mixtures and their salts as well as the hydrates of the salts, particularly their physiologically compatible salts having inorganic or organic acids, to medicaments containing these compounds, to their use, and to methods for the production thereof.

L'invention concerne des antagonistes CGRP de formule (I), dans laquelle A, X, D, E, G, M, Q et R?1¿ à R?3¿ sont spécifiés dans la revendication 1, leurs tautomères, leurs isomères, leurs diastéréomères, leurs énantiomères, leurs hydrates, leurs mélanges et leurs sels, ainsi que les hydrates de leurs sels, en particulier leurs sels physiologiquement supportables avec des acides inorganiques ou organiques. L'invention concerne également des médicaments contenant lesdits composés, leur utilisation et des procédés de production associés.

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