Semi-synthetic route for the preparation of paclitaxel,...

Details Semi-synthetic route for the preparation of paclitaxel,... Semi-synthetic route for the preparation of paclitaxel,...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2549951

An improvement has been provided in the preparation of docetaxel. This improvement process involves the conversion of 9-dihydro-13-acetylbaccatinIII to docetaxel by the step of removing the docetoxyl protective side chain from 7-O-triethylsilyl-9,10--diketodocetaxel.

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