Separation medium

B - Operations – Transporting – 01 – J

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B01J 20/22 (2006.01) B01J 20/32 (2006.01) C07C 227/34 (2006.01)

Patent

CA 1306988

ABSTRACT OF THE DISCLOSURE A separation medium useful as an adsorbent of liquid chromatography for optical resolution of racemic mixtures is disclosed, which comprises a reversed phase support coated with an optically active amino acid derivative represented by formula (I): Image (I) wherein R1 represents a straight or branched alkyl group having from 1 to 3 carbon atoms: and R2 and R3 each represents a straight or branched alkyl group having from 4 to 12 carbon atoms which may contain an aromatic group or an unsaturated alkyl group. The separation medium is applicable to optical resolution of a wide range of DL-amino acids and exhibits excellent durability.

572591

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