Short interfering rna molecules directed towards a tissue...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 31/7088 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2475447

The present invention relates to synthesised RNAs, more specific short interfering RNAs (siRNAs) that are able to modulate the expression of Tissue Factor (TF), as well as to a pharmaceutical preparation comprising the synthesised siRNA(s) and use thereof.

La présente invention concerne de ARN de synthèse, et plus particulièrement des ARN à interférences courtes (siRNA) capable de moduler l'expression du facteur tissulaire (TF). L'invention concerne également une préparation pharmaceutique à base d'ARN à interférences courtes, ainsi que son utilisation.

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