Single-chain multivalent binding proteins with effector...

Details Single-chain multivalent binding proteins with effector... Single-chain multivalent binding proteins with effector...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2654317

Multivalent binding peptides, including bi-specific binding peptides, having immunoglobulin effector function are provided, along with encoding nucleic acids, vectors and host cells as well as methods for making such peptides and methods for using such peptides to treat or prevent a variety of diseases, disorders or conditions, as well as to ameliorate at least one symptom associated with such a disease, disorder or condition.

La présente invention concerne des peptides de liaison polyvalents, y compris des peptides de liaison bi-spécifiques, dotés d'une fonction d'effecteur d'immunoglobuline. L'invention concerne également des acides nucléiques les encodant, des vecteurs et des cellules hôtes, ainsi que des procédés de fabrication desdits peptides et des procédés d'utilisation desdits peptides pour traiter ou prévenir une variété de maladies, de troubles ou de pathologies, ainsi qu'améliorer au moins un symptôme associé à telle maladie, tel trouble ou telle pathologie.

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