Skin permeation enhancer compositions comprising glycerol...

A - Human Necessities – 61 – K

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A61K 47/14 (2006.01) A61K 9/70 (2006.01) A61K 31/215 (2006.01) A61K 31/565 (2006.01) A61K 31/57 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2221096

Compositions, devices, and methods for trans-dermal administration of an active agent are dis-closed using a novel dual permeation enhancer mix-ture comprising lauryl acetate and a monoglyceride, preferably glycerol monolaurate. The dual perme-ation enhancer mixture comprising lauryl acetate is a potent permeation enhancer and provides stable sys-tems which are more readily characterized.

L'invention concerne des compositions, des dispositifs et des méthodes pour l'administration transdermique d'un agent actif, dans lesquels un nouveau mélange double stimulateur de perméation comprenant de l'acétate de lauryle et un monoglycéride, de préférence, du monolaurate de glycérol est utilisé. Le mélange double stimulateur de perméation renfermant de l'acétate de lauryle est un stimulateur de perméation puissant et fournit des systèmes stables qui sont plus facilement caractérisés.

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