Small molecule thienopyrimidine-based protein tyrosine...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01)

Patent

CA 2572308

Various thienopyrimidine-based analog compounds are able to selectively inhibit the Src family of tyrosine kinases. These compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections (I).

Différents composés analogues à base de thiénopyrimidine sont capables d'inhiber sélectivement la famille Src des tyrosine kinases. Ces composés sont utiles dans le traitement de différentes maladies dont des maladies hyperprolifératives, des maladies hématologiques, l'ostéoporose, des maladies neurologiques, des maladies auto-immunes, des maladies allergiques/immunologiques ou des infections virales (I).

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