Sphingosine-1-phosphate receptor agonist and antagonist...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 229/48 (2006.01) A61K 31/13 (2006.01) A61K 31/19 (2006.01) A61K 31/197 (2006.01) A61K 31/343 (2006.01) A61K 31/397 (2006.01) A61K 31/40 (2006.01) A61K 31/4192 (2006.01) A61K 31/661 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07C 49/753 (2006.01) C07C 59/54 (2006.01) C07C 215/00 (2006.01) C07C 217/00 (2006.01) C07C 217/74 (2006.01) C07C 229/14 (2006.01) C07C 255/46 (2006.01) C07D 205/04 (2006.01) C07D 207/08 (2006.01) C07D 249/06 (2006.01) C07D 263/52 (2006.01) C07D 307/79 (2006.01) C07F 9/09 (

Patent

CA 2672727

The present invention is directed to novel, potent, and selective agents, which are agonists or antagonists of the one or more of the individual receptors of the S1P receptor family. The compounds of the invention are useful as therapeutics for treating medical conditions associated with agonism or antagonism of the individual receptors of the S1P receptor family.

L'invention concerne de nouveaux et puissants agents sélectifs étant des agonistes ou des antagonistes d'un ou plusieurs récepteurs individuels de la famille des récepteurs de S1P. Les composés selon l'invention servent d'agents thérapeutiques pour traiter des troubles médicaux associés à l'agonisme ou à l'antagonisme des récepteurs individuels de la famille des récepteurs de S1P.

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