A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/279
A61K 31/13 (2006.01)
Patent
CA 2007507
A medicament for inhibiting growth of human and animal cells comprising: (1) a cell growth inhibitory amount of a one or more growth inhibitors comprising synthetically prepared sphingosine, synthetically prepared N-methyl-sphingosine or pharmaceutically acceptable salts thereof; and (2) a pharmaceutically acceptable carrier, diluent or excipient. A method for inhibiting growth of human and animal cells in vivo comprising contacting said cells with a cell growth inhibitory amount of one or more growth inhibitors comprising synthetically prepared sphingosine, synthetically prepared N-methyl-sphingosine or pharmaceutically acceptable salts thereof. A medicament for inhibiting growth of human and animal cells comprising: (1) A cell growth inhibitory amount of one or more growth inhibitors comprising sphingosine prepared from naturally occurring sphingolipid, N-methyl-sphingosine prepared from naturally occurring sphingolipid or pharmaceutically acceptable salts thereof; and (2) a pharmaceutically acceptable carrier, diluent or excipient. A method of inhibiting growth of human and animal cells i vivo comprising contacting said cells with a cell growth inhibitory amount of one or more growth inhibitors comprising sphingosine prepared from naturally occurring sphingolipid, N-methyl-sphingosine prepared from naturally occurring sphingolipid or pharmaceutically acceptable salts thereof. - 62 -
Médicament pour empêcher la croissance de cellules humaines et animales, renfermant : 1) une quantité inhibitrice de la croissance cellulaire, d'un ou de plusieurs inhibiteurs comprenant la sphingosine synthétique, la N-méthylsphingosine également synthétique, ou les sels acceptables en pharmacie; 2) un véhicule, diluant ou excipient acceptable en pharmacie. Méthode pour empêcher la croissance de cellules humaines et animales in vivo, consistant à mettre des cellules en contact avec une quantité inhibitrice de la croissance, d'un ou de plusieurs inhibiteurs comprenant la sphingosine synthétique, la N-méthylsphingosine également synthétique, ou les sels acceptables en pharmacie. Médicament pour empêcher la croissance de cellules humaines et animales, renfermant : 1) une quantité inhibitrice de la croissance cellulaire, d'un ou de plusieurs inhibiteurs comprenant la sphingosine naturelle, la N-méthylsphingosine également naturelle ou ses sels acceptables en pharmacie; 2) un véhicule, diluant ou excipient acceptable en pharmacie. Méthode pour empêcher la croissance de cellules humaines ou animales in vivo, consistant à mettre les cellules en contact avec une quantité inhibitrice de la croissance, d'un ou de plusieurs inhibiteurs comprenant la sphingosine préparée à partir d'un sphingolipide naturel, la N-méthylsphingosine également préparée à partir d'un sphingolipide naturel, ou ses sels acceptables en pharmacie.
Fujita Shuji
Hakomori Sen-Itiroh
Igarashi Yasuyuki
Ito Masayoshi
Ogawa Tomoya
Cornell Research Foundation Inc.
Fujita Shuji
G. Ronald Bell & Associates
Hakomori Sen-Itiroh
Igarashi Yasuyuki
LandOfFree
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