Spiro-indole derivatives for the treatment of parasitic...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 471/20 (2006.01) A61K 31/407 (2006.01) A61K 31/424 (2006.01) A61K 31/437 (2006.01) A61K 31/438 (2006.01) A61K 31/55 (2006.01) A61P 33/02 (2006.01) A61P 33/06 (2006.01) C07D 487/20 (2006.01) C07D 498/22 (2006.01)

Patent

CA 2719365

The invention relates to organic compounds which have interesting pharmaceutical properties. In particular, the compounds are useful in the treatment and/or prevention of infections such as those caused by Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Trypanosoma cruzi and parasites of the Leishmania genus such as, for example, Leishmania donovani. The invention also relates to pharmaceutical compositions containing the compounds, as well as processes for their preparation.

Linvention concerne des composés organiques qui présentent des propriétés pharmaceutiques intéressantes. En particulier, les composés sont utiles dans le traitement et/ou la prévention dinfections telles que celles causées par Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale, Trypanosoma cruzi et des parasites du genre Leishmania tels que, par exemple, Leishmania donovani. Linvention concerne également des compositions pharmaceutiques contenant les composés, ainsi que des procédés pour leur préparation.

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