A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/44 (2006.01)
Patent
CA 2487889
The invention relates to a stabilised pharmaceutical composition comprising a pharmaceutically active substance poorly soluble in water, a solubilising agent with a low content of both basic and acidic compounds and a polar organic solvent, in particular a stabilised injection concentrate, methods for preparing such stabilised pharmaceutical compositions and the use of a solubilising agent with a low content of both basic and acidic compounds to stabilise pharmaceutical compositions for pharmaceutically active substances.
La présente invention concerne une composition pharmaceutique stabilisée comprenant un principe pharmaceutiquement actif faiblement soluble dans l'eau, un agent solubilisant avec un faible contenu en composés acide et basique et un solvant organique polaire, en particulier un concentré d'injection stabilisé, des techniques de préparation de ces compositions pharmaceutiques et l'utilisation d'un agent solubilisant avec un faible contenu de composés acide et basique destiné à stabiliser des compositions pharmaceutiques à principes pharmaceutiquement actifs.
Cigankova Marie
Cirkva Ales
Kubat Martin
Kysilka Vladimir
Pospisilik Karel
Borden Ladner Gervais Llp
Pliva-Lachema A.s.
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