Stabilized p53 peptides and uses thereof

Details Stabilized p53 peptides and uses thereof Stabilized p53 peptides and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 7/54 (2006.01)

Patent

CA 2677045

Cross-linked peptides related to human p53 and bind to HMD2 or a family member of HDM2 useful for promoting apoptosis, e.g., in the treatment of and identifying therapeutic agents that binding to HMD2 or a family member of HDM2.

La présente invention concerne des peptides réticulés apparentés au peptide p53 humain qui se lient à HDM2 ou à un membre de la famille de HDM2 et se révèlent utiles pour ce qui est de promouvoir l'apoptose, par exemple dans le traitement et l'identification d'agents thérapeutiques se liant à HDM2 ou à un membre de la famille de HDM2.

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