Stabilized plasminogen activator precursor and method of...

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A61K 47/10 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/18 (2006.01) C12N 9/72 (2006.01) C12N 9/96 (2006.01)

Patent

CA 1283047

Abstract of the Disclosure A plasminogen activator precursor obtainable from a serum-free culture fluid of human kidney cells is stabilized by adding to its solution gelatin, poly-C1- C5-alkylene glycols, polyethylene-polyoxypropylene copolymers, mandelic acid salts, triethanolamine, acid addition salts of acetylglycillysine methyl ester, guanidine salts, thiocyanic acid salts, alkali metal iodides or serine.

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