Stable compositions for parenteral administration and their use

Details Stable compositions for parenteral administration and their use Stable compositions for parenteral administration and their use

A - Human Necessities

61

K

A61K 31/35 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 31/70 (2006.01)

Patent

CA 2074348

The invention relates to cartels stable microsphers compositions containing a fat or was or mixture thereof: an active ingredient selected from LL-F28249.alpha.-.lambda. compounds, 23-oxo and 23-imino derivatives of LL-F28249.alpha.-.lambda. compounds, milbemycin compounds and avermectin compounds; an oil, semi-soft fat, fatty acid derivative or mixture thereof; and an antioxidant. The invention also relates to a method for introducing and maintaining levels of the active compound in the blood of warm-blooded animals for extended periods of time and for the prevention or treatment of infections and infestations caused by helminths, nematodes, acarids and endo- and ectoparasitic arthropods in warm-blooded animals by the parenteral administration of compositions of the invention.

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