C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/56 (2006.01) A61K 31/55 (2006.01) C07H 15/252 (2006.01) C07H 17/00 (2006.01) C12P 17/18 (2006.01)
Patent
CA 2171116
A substance IT-62-B represented by the following formula (1): ( 1 ) Image a production process thereof, a medicinal composition comprising the compound as an active component, and methods of treating an infectious disease caused by bacteria and a tumor, in which such a substance is administered. The compound according to the invention has good antibacterial activities against gram-positive bacteria and some of gram-negative bacteria, and also possesses excellent antitumor activities against tumors such as human nasopharyngeal carcinoma, and is hence useful as a medicine.
L'invention se rapporte à une substance IT-62-B représentée par la formule (1), à son procédé de production, à une composition médicinale la contenant sous forme de principe actif, et à un procédé de traitement de maladies infectieuses et de tumeurs induites par des bactéries consistant à administrer cette substance. Le composé présente des activités antibactériennes contre les bactéries Gram positif et une partie des bactéries Gram négatif, et présente également une excellente activité antitumorale contre, par exemple, le cancer rhino-pharyngien chez l'homme, et est par conséquent utile comme médicament.
Chen Ru-Xian
Huang Ming-Yu
Kawauchi Takashi
Matsumoto Hiroshi
Otani Toshio
Gowling Lafleur Henderson Llp
Taiho Pharmaceutical Co. Ltd.
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