C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/10 (2006.01) A61K 31/381 (2006.01) A61P 35/00 (2006.01) C07D 333/10 (2006.01) C07D 409/12 (2006.01)
Patent
CA 2757573
Substituted 4-amino-5-benzoyl-2-(phenylamino)thiophene-3-carbonitriles and substituted 4-amino-5-benzoyl-2-(phenylamino)thiophene-3-carboxamides and their salts are tubulin polymerization inhibitors, useful in the treatment of cancer.
Les 4-amino-5-benzoyl-2-(phénylamino)thiophène-3-carbonitriles substitués et 4-amino-5-benzoyl-2-(phénylamino)thiophène-3-carboxamides substitués ci-décrits et leurs sels sont des inhibiteurs de polymérisation de la tubuline, utiles dans le traitement du cancer.
Beroza Paul P.
Damodaran Komath V.
Lui Stella
Ma Wenli
Wang Zhuo
Dennison Associates
Telik Inc.
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