Substituted aromatic compounds and pharmaceutical uses thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 57/30 (2006.01) A61K 31/192 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61P 13/12 (2006.01) A61P 29/00 (2006.01) C07C 57/58 (2006.01) C07C 59/48 (2006.01) C07C 59/52 (2006.01) C07C 61/39 (2006.01) C07D 213/55 (2006.01) C07D 257/04 (2006.01)

Patent

CA 2761018

The present invention relates to substituted aromatic compounds of Formula (I) and their pharmaceutical uses. Particular aspects of the invention relate to the use of those compounds in the prevention and/or treatment of various diseases and conditions in subjects, including the prevention or treatment of (i) blood disorders, (ii) renal disorders, nephropathies, or renal disorder complications; (iii) inflammatory-related diseases; and/or (iv) oxidative stress related disorders.

L'invention concerne des composés aromatiques substitués, représentés par la formule (I), et leurs utilisations pharmaceutiques. Des aspects particuliers de l'invention concernent l'utilisation de ces composés pour prévenir et/ou traiter diverses maladies et divers états pathologiques chez des sujets, y compris pour prévenir ou traiter (1) des troubles sanguins, (2) des troubles rénaux, une néphropathie ou des complications rénales; (3) des maladies associées à des états inflammatoires; et/ou (4) des troubles liés au stress oxydatif.

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