Substituted aryl piperazines as neurokinin antagonists

Details Substituted aryl piperazines as neurokinin antagonists Substituted aryl piperazines as neurokinin antagonists

C - Chemistry, Metallurgy

07

D

C07D 295/15 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) C07D 213/63 (2006.01) C07D 213/64 (2006.01) C07D 213/65 (2006.01) C07D 213/74 (2006.01) C07D 233/61 (2006.01) C07D 239/48 (2006.01) C07D 241/20 (2006.01) C07D 249/08 (2006.01) C07D 257/04 (2006.01) C07D 295/125 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 473/18 (2006.01) C07D 475/00 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2199621

Disclosed are substituted aryl piperazines of Formula (I) which are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis. In particular compounds of Formula (I) are shown to be neurokinin antagonists.

La présente invention concerne des pipérazines à substitution aryle représentées par la formule générale (I). Ces pipérazines qui sont des antagonistes du récepteur de la tachykinine conviennent avantageusement au traitement des affections inflammatoires, de la douleur ou de la migraine, de l'asthme et du vomissement. En l'occurrence, les composés représentés par la formule générale (I) sont des antagonistes avérés de la neurokinine.

Affiliated with

Also associated with

Rating

Substituted aryl piperazines as neurokinin antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted aryl piperazines as neurokinin antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted aryl piperazines as neurokinin antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1531287