C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 257/18 (2006.01) A61K 31/195 (2006.01) A61K 31/215 (2006.01) A61K 31/695 (2006.01) C07C 259/06 (2006.01) C07C 275/16 (2006.01) C07C 311/46 (2006.01) C07C 317/32 (2006.01) C07C 317/50 (2006.01) C07C 323/41 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2115432
Novel substituted beta-amino acid; derivatives having general formula (I), are provided, in which e.g. R2 is selected from the group consisting of hydrogen, lower alkyl radicals, lower alkenyl radicals, lower alkynyl radicals, alicyclic hydrocarbon radicals, aromatic hydrocarbon radicals, wherein said radicals are optionally substituted with hydroxy, lower alkoxy, lower alkyl, halogen, nitro, cyano, azido, ureido, ureylene, carboxyl or carbonyl derivatives, trifluoromethyl, acyloxy, alkylthio, arylthio, alkylsulfenyl, arylsulfenyl, alkylsulfonyl, arylsulfonyl, amino, alkylamino, trialkylsilyl, aminosulfonyl, dialkylami- no, alkanoylamino, aroylamino, phenyl, naphtyl, lower alkynyl which are optionally substituted with one or more of the fol- lowing: halogen, nitro, lower alkoxy, lower alkyl, trialkylsilyl, azide and phenyl; the invention also pertains to pharmaceuti- cal compositions comprising such derivatives:
Bovy Philippe Roger
Rico Joseph Gerace
Rogers Thomas Edward
Tjoeng Foe Siong
Zablocki Jeffery Alan
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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