C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07D 471/14 (2006.01)
Patent
CA 2571360
Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
L'invention concerne des systèmes de noyaux d'imidazo-quinoline, -pyridine, et naphthyridine (en particulier des quinolines, tétrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tétrahydronaphthyridines) substitués sur leur position 1 par un substituant cyclique, des compositions pharmaceutiques contenant lesdits composés, des procédés de fabrication desdits composés, et des procédés d'utilisation de ces composés en tant qu'immunomodulateurs, permettant d'induire la biosynthèse de la cytokine chez les animaux et dans le traitement des maladies notamment les maladies virales et néoplasiques.
Amos David T.
Bonk Jason D.
Dellaria Joseph F. Jr.
Dressel Luke T.
Radmer Matthew R.
3m Innovative Properties Company
Robic
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