Substituted n-acyl-2-aminothiazoles

Details Substituted n-acyl-2-aminothiazoles Substituted n-acyl-2-aminothiazoles

C - Chemistry, Metallurgy

07

D

C07D 277/60 (2006.01) A61K 31/428 (2006.01) A61K 31/429 (2006.01) A61P 1/12 (2006.01) A61P 3/10 (2006.01) A61P 11/06 (2006.01) C07D 277/84 (2006.01)

Patent

CA 2575339

The invention is concerned with novel substituted N-acyl-2-aminothiazoles of the formula (I) wherein R, Ri and X are as defined in the specification and claims, as well as pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of diabetes, diabetic retinopathy, asthma and diarrhea.

L~invention concerne de nouveaux aminothiazoles substitués N-acyle-2-de la formule (I) dans laquelle R, Ri et X sont définis tels que dans la spécification et les revendications ainsi que les sels de ceux-ci, pharmaceutiquement acceptables. Ces composés sont utiles dans le traitement du diabète, de la rétinopathie diabétique, de l~asthme et de la diarrhée.

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