Substituted phenylacetic acids as dp-2 antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 295/16 (2006.01) A61P 11/06 (2006.01) A61P 37/08 (2006.01) C07D 207/273 (2006.01) C07D 211/72 (2006.01) C07D 225/02 (2006.01) C07D 233/96 (2006.01) C07D 295/185 (2006.01) C07D 295/21 (2006.01)

Patent

CA 2654784

Substituted phenyl acetic acid compounds of formula (I), pharmaceutical compositions, methods for their preparation and methods are provided that are useful in the treatment and prevention of disorders or conditions responsive to DP 2 receptor modulation, in particular, inflammatory and immune related disorders and conditions, such as asthma, allergic rhinitis and atopic dermatitis.

La présente invention concerne des composés d'acide phénylacétique substitués répondant à la formule (I), des compositions pharmaceutiques, des procédés pour leur préparation et des procédés qui se révèlent utiles pour le traitement et la prévention de troubles ou de pathologies sensibles à une modulation des récepteurs de DP-2, en particulier, des troubles et des pathologies inflammatoires et immunitaires, tels que l'asthme, la rhinite allergique et la dermatite atopique.

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