Substituted pyrazole compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 403/12 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2622352

Disclosed are protein kinase inhibitors, compositions comprising such inhibitors, and methods of use thereof. More particularly, disclosed are inhibitors of Aurora A (Aurora-2) protein kinase. Also disclosed are methods of treating diseases associated with protein kinases, especially diseases associated with Aurora-2, such as cancer.

L'invention concerne des inhibiteurs de protéines kinases, des compositions comprenant de tels inhibiteurs, et des méthodes d'utilisation associées. En particulier, l'invention concerne des inhibiteurs de la protéine kinase Aurora A (Aurora-2). L'invention concerne également des méthodes de traitement de maladies associés à des protéines kinases, en particulier des maladies associées à Aurora-2, notamment, le cancer.

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