C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/242, 260/328
C07D 495/04 (2006.01) A61K 31/38 (2006.01)
Patent
CA 1320493
264/WHN11 TITLE OF THE INVENTION 5-[N-METHOXYETHYL-N-METHOXYETHOXYETHYL)AMINOMETHYL]- THIENO[2,3-b]THIOPHENE-2-SULFONAMIDE AS ANTIGLAUCOMA AGENTS ABSTRACT OF THE DISCLOSURE This invention relates to novel aromatic sulfonamides useful in the treatment of elevated intraocular pressure. More particularly this invention relates to the compounds having the structural formula: Image 264/WHN11 -i- 17554IB as well as the pharmaceutically and ophthalmo- logically acceptable salts thereof. This invention also relates to pharmaceutical compositions and the use thereof for systemic and ophthalmic use employing the novel compound of this invention as active ingredient for the treatment of elevated intraocular pressure, especially when accompanied by pathological damage such as in the disease known as glaucoma. The invention also relates to processes for preparation of the novel compound.
615342
Hartman George D.
Prugh John D.
Hartman George D.
Merck & Co. Inc.
Prugh John D.
Swabey Ogilvy Renault
LandOfFree
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