C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/04 (2006.01) A61K 31/495 (2006.01) A61P 25/18 (2006.01) C07C 35/32 (2006.01) C12P 7/02 (2006.01)
Patent
CA 2536144
4-((1R,3S)-6-Chloro-3-phenylindan-1-yl)-1,2,2-trimethylpiperazine hydrogen succinate or hydrogen malonate, pharmaceutical compositions containing these salts and the medical use thereof, including for the treatment of schizophrenia and other psychotic disorders. Also described are methods for the preparation of 4-((1R,3S)-6-Chloro-3-phenylindan- 1-yl)- 1,2,2-trimethylpiperazine and medical uses thereof.
L'invention concerne un hydrogène succinate ou un hydrogène malonate de 4-((1R,3S)-6-Chloro-3-phénylindan-1-yl)-1,2,2-triméthylpipérazine, des compositions pharmaceutiques contenant ces sels, ainsi que leur utilisation thérapeutique, notamment dans le traitement de la schizophrénie et d'autres troubles psychotiques. L'invention concerne également des méthodes de préparation de 4-((1R,3S)-6-Chloro-3-phénylindan-1-yl)-1,2,2-triméthylpipérazine, ainsi que ses utilisations thérapeutiques.
Bang-Andersen Benny
Dahl Allan Carsten
Howells Mark
Lopez de Diego Heidi
Lyngso Lars Ole
Goudreau Gage Dubuc
H. Lundbeck A/s
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