Sulfonamide derivatives useful as liver carnitine palmitoyl...

Details Sulfonamide derivatives useful as liver carnitine palmitoyl... Sulfonamide derivatives useful as liver carnitine palmitoyl...

C - Chemistry, Metallurgy

07

C

C07C 311/21 (2006.01) A61K 31/196 (2006.01) A61K 31/42 (2006.01) A61K 31/505 (2006.01) A61P 3/10 (2006.01) C07C 311/29 (2006.01) C07D 409/04 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2608837

The invention is concerned with novel sulfonamide derivatives of Formula (I); wherein R2, R3, R4, A, X, Y1, Y2, Y3, Y4 and Z1 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.

L~invention concerne des dérivés de sulfonamide originaux de formule (I) où R2, R3, R4, A, X, Y1, Y2, Y3, Y4 et Z1 sont tels que définis dans la description et dans les revendications, de même que des sels et esters de ceux-ci acceptables sur le plan physiologique. Ces composés inhibent la L-CPT1 et peuvent être utilisés comme médicaments.

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