C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/33 (2006.01) A61K 31/506 (2006.01) A61P 35/00 (2006.01) C07D 239/48 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)
Patent
CA 2684447
The present invention relates to a compound of the formula (I) wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
La présente invention porte sur un composé de la formule (I) dans laquelle R1 à R6, A, B, n et m sont tels que définis ici. De tels nouveaux dérivés de sulfonyle amide sont utiles dans le traitement d'une croissance cellulaire anormale, telle que le cancer, dans les mammifères. Cette invention porte également sur un procédé d'utilisation de tels composés dans le traitement d'une croissance cellulaire anormale dans les mammifères, notamment les êtres humains, et sur des compositions pharmaceutiques contenant de tels composés.
Autry Christopher Lowell
Bhattacharya Samit Kumar
Freeman-Cook Kevin Daniel
Hayward Matthew Merrill
Hulford Catherine Angela
Pfizer Products Inc.
Smart & Biggar
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