Sustained release compositions

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 307/24 (2006.01) A61K 47/22 (2006.01) C07D 309/08 (2006.01) C07D 309/10 (2006.01)

Patent

CA 1337431

A novel sustained release composition is provided herein. The composition includes: (I) a biologically- active substance; and (II) a specific monomeric compound which is obtainable by reacting: (if required, in the presence of a Bronsted acid or a Lewis acid) (a) at least one acidic, neutral or amphoteric organic compound which contains one or more active hydrogen atom-containing groups and which may be otherwise substituted or unsubstituted, or which may be saturated or may be unsaturated, with a least one olefinic bond of (b) at least one olefinically unsaturated cyclic ether of the formula: Image in which: R1, R2, R4, and R5 are as specifically defined in the disclosure.

475963

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