Synthesis of beta-lactams using a metal compound

Details Synthesis of beta-lactams using a metal compound Synthesis of beta-lactams using a metal compound

C - Chemistry, Metallurgy

07

D

260/277, 260/335

C07D 205/08 (2006.01) C07D 205/085 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07F 3/06 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2019619

Abstract A synthesis of trans-.beta.-lactams with an easily convert- ible group on the C-4 carbon atom of the azetidinone ring comprising a condensation reaction of a metal enolate with an imine with a heterocyclic group or a diimine is provided. Furthermore, new chiral .beta.-lactams and an enantioselect- ive synthesis of .beta.-lactams using a chiral imine or .beta.-diimine are provided. Also new chiral substituted amino propionic ester metal compounds and new chiral amino acid compounds and processes for the preparation thereof are provided.

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