Systems, devices and methods of treatment of intervertebral...

Details Systems, devices and methods of treatment of intervertebral... Systems, devices and methods of treatment of intervertebral...

A - Human Necessities

61

F

A61F 2/44 (2006.01)

Patent

CA 2588388

A bioactive/biodegradable nucleus implant for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant is inflated with a high molecular weight fluid, gel or combination of fluid and elastomer, preferably an under-hydrated HA hydrogel/growth factor mixture with or without host cells. The implant includes an internal, integral, self-sealing valve that allows one-way filling of the implant after it is placed within the disc, and is made from a material that allows fibrous in growth thereby stabilizing the implant. A variety of substances can be incorporated into the implant to promote healing, prevent infection, or arrest pain.

L'invention concerne un implant bioactif/biodégradable de noyau permettant de réparer des disques intervertébraux dégénérés. Cet implant est gonflé à l'intérieur de l'espace du noyau après élimination du noyau dégénéré, aux fins de remise sous pression de l'espace du noyau dans le disque intervertébral. L'implant est gonflé au moyen d'un fluide à poids moléculaire élevé, d'un gel ou d'une combinaison de fluide et d'élastomère, de préférence un mélange d'hydrogel de HA sous-hydraté/facteur de croissance avec ou sans cellules hôtes. L'implant comporte une vanne interne, monobloc, à auto-étanchéité permettant le remplissage monodirectionnel de l'implant une fois placé dans le disque et est conçu dans un matériau permettant l'expansion des fibres aux fins de stabilisation de l'implant. On peut incorporer diverses substances en vue de favoriser la guérison, de prévenir l'infection ou d'arrêter la douleur.

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