T cell antigen receptor v region proteins and methods of...

Details T cell antigen receptor v region proteins and methods of... T cell antigen receptor v region proteins and methods of...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/725 (2006.01) C12N 15/70 (2006.01) G01N 33/564 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2181171

The present invention relates to the production of full length T cell antigen receptor V region proteins. The invention provides for methods of expressing the proteins as well as expression vectors for enhanced production of full length T cell antigen receptor V region proteins. The invention further provides for the V.beta.5.3 region protein. The proteins of the invention have uses in the diagnosis and therapy of immune-related disorders.

La présente invention se rapporte à la production de protéines entières de la région V du récepteur d'antigène des lymphocytes T. L'invention se rapporte également à des procédés d'expression des protéines ainsi qu'aux vecteurs d'expression destinés à améliorer la production des protéines entières de la région V du récepteur d'antigène des lymphocytes T. L'invention se rapporte en outre à la protéine de la région V.beta.5.3. Les protéines de l'invention sont utilisées dans le diagnostic et la thérapie de troubles relatifs au système immun.

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