Tablet and granulate containing mesna as active substance

Details Tablet and granulate containing mesna as active substance Tablet and granulate containing mesna as active substance

A - Human Necessities

61

K

A61K 31/185 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/46 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2047027

The invention relates to a tablet and to a granulate as well as to a process for their manufacture containing mesna as active substance, where the tablet in each case related to one part by weight of mesna contains 0.01 - 1 parts by weight of a binding agent, 0.03 - 0.4 parts by weight of a disintegrant, 0.01 - 0.2 parts by weight of a lubricant and 0.1 - 1 parts by weight of a filling agent as well as, in the case of an effervescent tablet, an additional 0.05 - 30 parts by weight of a conventional physiologically acceptable effervescent mixture, the granulate containing the same previously mentioned auxiliary substances with the exception of the disintegrant. The tablets have good stability, are easy to take, and are virtually tasteless if swallowed immediately.

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