Targeted immunogens

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/7088 (2006.01) A61K 35/14 (2006.01) A61K 38/17 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) C07K 14/47 (2006.01) C07K 19/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2477429

The present invention provides reagents and methods for producing and utilizing targeted immunogens. In preferred embodiments, an immunogen is conjugated to an amino acid sequence that targets the immunogen to the MHC presentation pathway. Using the reagents and methods provided herein, immunization protocols may be enhanced resulting in increased immunity of the host.

La présente invention concerne des agents réactifs et des procédés de production et d'utilisation d'immunogènes ciblés. Dans des modes de réalisation préférés, un immunogène est conjugué à une séquence d'acides aminés qui ciblent l'immunogène à la voie de présentation du complexe majeur d'histocompatibilité CMH. Au moyen des agents de réaction et des procédés décrits, les protocoles d'immunisation peuvent être améliorés, ce qui assure une meilleure immunité de l'hôte.

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