C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 303/02 (2006.01) A61K 31/145 (2006.01)
Patent
CA 2593563
The quantitatively most important pathway for the excretion of cholesterol in mammals is the formation of bile salts (the conjugate bases of bile acids). The major bile salts are synthesized and secreted by as glycine or taurine conjugates. Taurine (2 aminoethyl sulphonic acid) is naturally produced by the liver cells and central nervous system cells, it is neuroprotective and is a cholesterol lowering agent with virtually no recorded side effects.
La voie la plus importante, du point de vue quantitatif, d'excrétion du cholestérol chez les mammifères est la formation de sels biliaires (bases conjuguées des acides biliaires). La plupart des sels biliaires sont synthétisés et sécrétés sous forme de conjugués de glycine ou de taurine. La taurine (acide 2 aminoéthyl sulphonique), qui est produite naturellement par les cellules hépatiques et les cellules du système nerveux central, est neuroprotectrice et constitue un hypocholestérolémiant pratiquement dépourvu d'effets secondaires.
Abdalla Magd Ahmed Kotb
Goudreau Gage Dubuc
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