Taxol derivatives with antitumor activity

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 493/08 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2636211

Taxol derivatives or their salts having the formula as following: Wherein, R1, R2, Z1, Z2, Z3 and Z4 are defined as the description. Their preparation methods and their use as antitumor agent are also disclosed.

La présente invention concerne des dérivés de taxol ou des sels de ceux-ci, de formule (I) dans laquelle R1, R2, Z1, Z2, Z3 et Z4 sont tels que définis dans la description. Cette invention concerne également des procédés pour les préparer et leur utilisation comme agent antitumoral.

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