A - Human Necessities – 01 – K
Patent
A - Human Necessities
01
K
A01K 67/00 (2006.01) C12N 1/21 (2006.01) C12N 15/12 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2372251
Model systems of Alzheimer's disease comprise a DNA sequence encoding an amyloid precursor protein (APP) isoform or fragment that has an amino acid substitution. The substituted amino acid may be other than valine at the amino acid position corresponding to amino acid residue position 717 of APP770. Methods of determining genetic predisposition to Alzheimer's disease are also disclosed.
Chartier-Harlin Marie-Christine
Goate Alison Mary
Hardy John Anthony
Mullan Michael John
Owen Michael John
Imperial College Of Science Technology & Medicine
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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