Tetrahydrocarboline compounds as anticancer agents

Details Tetrahydrocarboline compounds as anticancer agents Tetrahydrocarboline compounds as anticancer agents

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01)

Patent

CA 2554150

Tetrahydrocarboline compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent. Methods of using the tetrahydrocarboline compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of proliferative diseases.

L'invention concerne des composés de tétrahydrocarboline, des sels pharmceutiquement acceptables et des promédicaments de ces composés; des compositions qui renferment un excipient pharmaceutiquement acceptable et un ou plusieurs composés de tétrahydrocarboline, seuls ou combinés avec au moins un agent thérapeutique additionnel. L'invention concerne des procédés utilisant les composés de tétrahydrocarboline, seuls ou en combinaison avec au moins un agent thérapeutique additionnel, pour prévenir ou traiter des maladies proliférantes.

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