Tetrahydroquinoxalines acting as bradykinin antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 241/50 (2006.01) A61K 31/498 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61P 29/00 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 513/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2454007

The invention relates to novel tetrahydroquinoxalines of structure I/Ia, to a method for producing the same and to the use thereof for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of painful conditions. The compounds have an affinity to the bradykinin-1 receptor.

La présente invention concerne de nouvelles tétrahydrochinoxalines de structure I/Ia, leur procédé de production et leur utilisation pour traiter et/ou prévenir des maladies, notamment pour traiter et/ou prévenir des états douloureux. Ces composés présentent une affinité par rapport au récepteur de bradykinine-1.

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