The lactose operon of lactobacillus delbrueckii and its use...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/31 (2006.01) A23C 9/123 (2006.01) C07K 14/335 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2378143

The present invention relates to a DNA sequence suitable for the controlled transcription and/or expression of a variety of different genes in bacteria, preferably gram positive bacteria. In particular the present invention pertains to a DNA sequence comprising the promoter and the gene coding for the lac repressor of the lac operon of Lactobacillus delbrueckii with a DNA sequence coding for a gene product of interest being arranged inbetween.

La présente invention concerne une séquence d'ADN qui convient pour la transcription et/ou l'expression contrôlée d'une variété de gènes différents de bactéries, de préférence des bactéries Gram positif. Cette invention concerne plus particulièrement une séquence d'ADN qui comprend le promoteur et le gène codant pour le répresseur de Lac de l'opéron de Lac de Lactobacillus delbrueckii avec une séquence d'ADN codante pour un produit génique recherché agencé entre les deux.

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