C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) G01N 33/53 (2006.01) G01N 33/82 (2006.01)
Patent
CA 2497884
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL- 1R1 are described.
L'invention concerne des anticorps qui interagissent avec le récepteur de type 1 de l'interleukine-1 (IL-1R1). L'invention concerne également des méthodes de traitement de maladies induites par l'IL-1, consistant à administrer une dose efficace sur le plan pharmaceutique d'anticorps contre IL-1R1. L'invention concerne enfin des méthodes permettant de détecter la concentration de IL-1R1 dans un échantillon à l'aide d'anticorps contre IL-1R1.
Elliott Gary
Huang Haichun
Martin Francis Hall
Qian Xueming
Varnum Brian
Amgen Inc.
Gowling Lafleur Henderson Llp
Medarex Inc.
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