Therapeutic methods using wrn binding molecules

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 498/20 (2006.01) A61K 31/5383 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2664433

The present invention provides, inter alia, compositions and methods for treating various diseases and disorders in a mammal by administering to a mammal in need an effective amount of a composition comprising a non-DNA small molecule that binds WRN, such as members of the spirooxindole (SPOX) class.

La présente invention concerne, entre autres, des compositions et des procédés destinés à traiter diverses maladies et divers troubles chez un mammifère en administrant à un mammifère en ayant besoin une quantité effective d'une composition comprenant une petite molécule n'étant pas de l'ADN qui se lie à WRN, comme des membres de la classe des spiro-oxindols (SPOX).

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