Therapeutic polypeptides, nucleic acids encoding same, and...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/04 (2006.01) A61K 38/17 (2006.01) C07H 21/02 (2006.01) C07K 14/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/00 (2006.01) C12P 21/02 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2481039

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

L'invention porte sur des séquences d'acides nucléiques codant de nouveaux polypeptides, ainsi que sur les polypeptides codés par ces séquences d'acides nucléiques et sur des anticorps qui se lient de manière immunospécifique au polypeptide, de même que sur des dérivés, des variants, des mutants ou des fragments de ce nouveau polypeptide, polynucléotide ou anticorps spécifique du polypeptide. L'invention porte également sur des méthodes thérapeutiques, diagnostiques et de recherche utilisées dans le diagnostic, le traitement et la prévention de troubles où interviennent l'un quelconque de ces nouveaux acides nucléiques et nouvelles protéines chez l'homme.

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