C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/36 (2006.01) A61K 38/45 (2006.01) A61K 38/55 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/545 (2006.01) C07K 14/705 (2006.01) C07K 14/745 (2006.01) C07K 14/775 (2006.01) C07K 14/81 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C07K 16/36 (2006.01) C07K 16/38 (2006.01) C07K 16/40 (2006.01) C07K 16/42 (2006.01) C12N 9/10 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) C12N 15/25 (2006.01) C12P
Patent
CA 2488547
Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
L'invention concerne des séquences d'acides nucléiques codant pour de nouveaux polypeptides. L'invention concerne également des polypeptides codés par ces séquences d'acides nucléiques, ainsi que des anticorps qui se lient de façon immunospécifique à ces polypeptides, de même que des dérivés, variants, mutants ou fragments de ces polypeptides, ces polynucléotides ou ces anticorps spécifiques à ces polypeptides. L'invention concerne par ailleurs des vecteurs, des cellules hôtes, des anticorps et des procédés recombinants pour produire ces polypeptides et polynucléotides, ainsi que des méthodes d'utilisation de ceux-ci. L'invention concerne enfin des méthodes thérapeutiques et diagnostiques et des méthodes de recherche destinées au diagnostic, au traitement et à la prévention de troubles liés à ces protéines et ces acides nucléiques humains.
Alsobrook John P. II
Alvarez Enrique
Anderson David W.
Boldog Ferenc L.
Casman Stacie J.
Boldog Ferenc L.
Casman Stacie J.
Catterton Elina
Chapoval Andrei
Crabtree-Bokor Julie R.
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